Genetics Research
rs502396
Population Frequencies12
African
C 0.68621T 0.31379CC 0.473565CT/TC 0.425281TT 0.101154pop=37,942
African American
C 0.68434T 0.31566CC 0.471551CT/TC 0.425582TT 0.102867pop=36,416
African Others
C 0.7307T 0.2693CC 0.521625CT/TC 0.418087TT 0.060288pop=1,526
Asian
C 0.74222T 0.25778CC 0.556429CT/TC 0.371581TT 0.07199pop=12,724
East Asian
C 0.74261T 0.25739CC 0.555942CT/TC 0.373333TT 0.070725pop=10,350
European
C 0.474106T 0.525894CC 0.224653CT/TC 0.498906TT 0.276441pop=348,146
Latin American 1
C 0.5208T 0.4792CC 0.268336CT/TC 0.50483TT 0.226834pop=5,590
Latin American 2
C 0.4275T 0.5725CC 0.180929CT/TC 0.493233TT 0.325838pop=9,606
Other
C 0.53334T 0.46666CC 0.292541CT/TC 0.481595TT 0.225864pop=12,388
Other Asian
C 0.7405T 0.2595CC 0.558551CT/TC 0.363943TT 0.077506pop=2,374
South Asian
C 0.5321T 0.4679CC 0.286131CT/TC 0.491971TT 0.221898pop=1,370
Studies29
Unread Studies29 ▼
1
… As frequências genotípicas do polimorfismo rs502396 não apresentaram o equilíbrio de Hardy–Weinberg e, por isso, as análises de associação deste SNP com a carcinogênese …
2
High-altitude (HA, 2500 m) hypoxic exposure evokes a multitude of physiological processes. The hypoxia-sensing genes though influence transcriptional output in disease …
3
After the completion of the Human Genome Project in 2003, the field of genetics has witnessed massive progress that spanned research in high-altitude biology also. Especially the …
4
… (C) The comparison of the plasma TYMS levels of patients with different genotypes at rs502396 locus. Seventy-four cases of genotype, 67 cases of genotype, and 9 cases of TT …
5
… Variation in TYMS (rs502396) is associated with reduced P16 protein expression and then related to breast carcinogenesis.[12] MicroRNAs (miRNAs) participate in various …
6
Recent discoveries indicate a genetic basis for high-altitude adaptation among human groups who have resided at high altitude for millennia, including Andeans, Tibetans, and …
7
Understanding the inter-individual variability in physical fitness performance has been the focus of scientific research for decades especially in the United States military. Injury and …
8
Using gene-specific and genome-wide epigenetic approaches, this project answers two main questions: 1) Is there an epigenetic contribution to high-altitude adaptation in the Andes? 2…
9
Neural tube defects (NTDs) are common and severe birth defects. These abnormalities arise early in development, likely before the mother is aware she is pregnant. It has been well …
10
O estudo da adaptação humana para vida em altas altitudes é um tema bastante abordado na literatura científica mundial, tanto no que se refere às adaptações genéticas, quanto às …
11
Thymidylate synthase (TYMS), a key rate-limiting enzyme in the folate metabolism, plays essential roles in the development of several malignancies including …
12
Single-nucleotide polymorphisms (SNPs) in one-carbon metabolism genes and lifestyle factors (alcohol drinking and breast folate) may be determinants of whole-genome methylation …
13
… was associated with higher p16 INK4a promoter methylation (OR = 2.66, 95% CI: 1.11–6.42 and OR = 2.72, 95% CI: 1.12–6.66, respectively), whereas variation in TYMS (rs502396) …
14
Genome-wide DNA hypomethylation is an early event in the carcinogenic process. Percent methylation of long interspersed nucleotide element-1 (LINE-1) is a biomarker of genome-…
15
We investigated the association between conotruncal heart defects (CTDs) and maternal and fetal single nucleotide polymorphisms (SNPs) in 60 genes in the folate, …
16
En aquest Treball de Final de Grau s’exposen els resultats de l’anàlisi de les dades genètiques del projecte EurGast2 "Genetic susceptibility, environmental exposure and gastric …
17
… The gene-folate interaction was associated with a reduced risk of NTDs for mothers in the low folate intake group with TYMS SNP rs502396 or rs699517 heterozygous genotype …
18
… TYMS rs502396 (Table 4); among men with the TYMS rs502396 CC genotype, … rs502396 and MTHFR rs12121543 (Table 4) exemplifies the finding that in men with the TYMS rs502396 …
19
In this study, we investigated whether the two TYMS functional variants (28 bp VNTR and 1494del6) (275 cases and 653 controls) and six selected SNPs (265 case infants, 535 control …
20
… found significant association between increased lung cancer risk and the minor allele of TYMS rs16948305 and rs699517 in never smokers, while the minor allele of TYMS rs502396 …
21
… CGFID_5067 and also provides primer and probe sequences for rs502396 …
22
Acute myeloid leukemia (AML) is a rapidly proliferating clonal disorder of hematopoietic stem cells. Since AML is a clinical and biological heterogenous disease, AML patients are …
23
Autosomal dominant spinocerebellar ataxias (SCAs) are clinically characterised by cerebellar ataxia often in combination with other signs like extrapyramidal symptoms, …
24
The hypothesis underlying this study is that variations in genes involved in methionine metabolism may contribute to genetic susceptibility for early-onset ischaemic stroke. We …
25
… Three of the five TYMS SNPs (rs284179, rs1001761, and rs502396) investigated here showed elevated risks for spina bifida for both heterozygote or homozygote individuals. This …
26
We comprehensively evaluated genetic variants in the thymidylate synthase (TYMS) gene in association with endometrial cancer risk in a population-based case-control study of 1,199 …
27
In a multicenter case‐control study of renal cell carcinoma (RCC) conducted in central and eastern Europe, we reported a strong inverse association with high vegetable intake and …
28
This study examines the response to dexamethasone–doxorubicin–vincristine (DAV) therapy, followed by conditioning regimen and autologous stem cells transplantation (ASCT) in …
29
بیان مساله تحقیق (Acute Lymphoblastic Leukemia) ALLلوسمی حاد لنفوبلاستیک شایعترین لوسمی کودکان می باشد. 25تا30درصد تمامی بدخیمی های کودکان را شامل می شود. اگرچه شمای …
Curated Studies0 ▼
These studies were determined to be useful for this variant — check "Unused Studies" further down if curious what didn't make the cut.
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Unused Studies0 ▼
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