Genetics Research
rs4920037
Population Frequencies12
African
G 0.8508A 0.1492GG 0.724763GA/AG 0.252065AA 0.023171pop=49,630
African American
G 0.85013A 0.14987GG 0.723615GA/AG 0.253029AA 0.023356pop=47,868
African Others
G 0.8689A 0.1311GG 0.755959GA/AG 0.22588AA 0.018161pop=1,762
Asian
G 0.9697A 0.0303GG 0.940629GA/AG 0.058142AA 0.00123pop=11,386
East Asian
G 0.9755A 0.0245GG 0.951919GA/AG 0.047199AA 0.000882pop=9,068
European
G 0.766193A 0.233807GG 0.58788GA/AG 0.356626AA 0.055494pop=544,060
Latin American 1
G 0.8291A 0.1709GG 0.686947GA/AG 0.284211AA 0.028842pop=9,500
Latin American 2
G 0.88387A 0.11613GG 0.78155GA/AG 0.204632AA 0.013818pop=15,198
Other
G 0.82138A 0.17862GG 0.677042GA/AG 0.288684AA 0.034274pop=17,798
Other Asian
G 0.9469A 0.0531GG 0.896462GA/AG 0.100949AA 0.002588pop=2,318
South Asian
G 0.8063A 0.1937GG 0.652316GA/AG 0.307905AA 0.039778pop=7,944
Studies34
Unread Studies34 ▼
1
This study aims to investigate genetic association between Non-syndromic Cleft lip with or without palate (NCLP) and 14 specific Single Nucleotide Polymorphism (SNPs) …
2
Исследование посвящено выявлению генетических маркеров, ассоциированных с повышенной личностной тревожностью среди 119 психически здоровых лиц, …
3
… conclusion, there was an indication that lung cancer risks might be highest in those with a high %MMA who also carried cystathionine β-synthase (CBS) rs234709 and rs4920037 …
4
… Pro259Arg) and of the single nucleotide polymorphism rs4920037, belonging to transcobalamin 2 (TCN2) and cystathionine beta-synthase (CBS), respectively [113,114]. Therefore, it …
5
Exposure to arsenic (As) is a major public health concern globally. Inorganic As (InAs) undergoes hepatic methylation to form monomethyl (MMAs)-and dimethyl (DMAs)-arsenical …
6
Orofacial clefts are the most common orofacial malformations in humans and include cleft lip (CL), cleft lip with or without cleft palate (CL/P), and cleft palate only (CPO). CPО (МІМ …
7
Environmental exposure to inorganic arsenic (InAs) is a considerable worldwide problem, and over 57 million people in Bangladesh have been chronically exposed to …
8
… Then, in order to verify the involvement of the same three polymorphisms (rs1801133 of MTHFR, rs1801198 of TCN2, and rs4920037 of CBS), our group investigated an independent …
9
… On the contrary, the same three polymorphisms (rs1801133 of MTHFR, rs1801198 of TCN2, and rs4920037 of CBS) investigated in independent samples of different ancestries showed …
10
… We included other MTHFR (rs1801131) and CβS polymorphisms (rs2124459, rs2851391 and rs4920037) based on their potential to modulate PLP or homocysteine concentrations. …
11
… Furthermore, variant genotypes for CBS SNPs (rs234709 and rs4920037) have been found to be associated with the level of urinary MMA and As-induced lung cancer according to two …
12
Arsenic (As) is a naturally occurring element classified as a human carcinogen on the basis of strong epidemiological evidence (IARC, 2004; ATSDR, 2008; IARC, 2009). It is released …
13
Arsenic exposure from drinking water has been associated with symptoms during pregnancy, as well as negative birth outcomes. The individual’s capability to methylate arsenic …
14
Exposure to inorganic arsenic (InAs) via drinking water and/or food is a considerable worldwide problem. Methylation of InAs generates monomethyl (MMAs III+V )- and dimethyl (DMAs …
15
Up to 200 million people in 70 countries are at risk from drinking water contaminated with arsenic, which is a major cause of chronic debilitating illnesses and fatal cancers. Until recently …
16
Orofacial clefts (OFCs) are one of the most common birth defects in humans. They are the subject of a number of investigations aimed at elucidating the bases of their complex …
17
… in our study, rs2124459 was in high LD with rs4920037 (D′=0.97) and rs234705 (D… , rs4920037 and rs234705 had significant nominal p values before Bonferroni correction (rs4920037…
18
Consumption of arsenic-contaminated drinking water adversely affects health. There is interindividual variation in arsenic metabolism efficiency, partially due to genetic …
19
… que los riesgos de cancer de pulmon podrian ser mas altos en aquellos con un alto % de MMA urinario y que tambien son portadores de las variantes alelicas rs234709 y rs4920037 …
20
We investigated the hypothesis that there are interactions between SNPs in folate metabolism pathway genes and environmental risk factors to the etiology of neural tube defects (…
21
Cystathionine β-synthase is an essential enzyme of the trans-sulfuration pathway that condenses serine with homocysteine to form cystathionine. Missense mutations in CBS are the …
22
The primary aims of this study were to (i) determine whether folate metabolism genetic polymorphisms predict age of onset and occurrence of late life depression; and (ii) …
23
To explore the association between 18 candidate genes encoding enzymes on the folate/homocysteine metabolism pathway and non-syndromic cleft lip with or without cleft …
24
The risk of colorectal cancer (CRC) may be influenced by aberrant DNA methylation and altered nucleotide synthesis and repair, possibly caused by impaired dietary folate intake as …
25
Leukemia is the most common childhood cancer, which is the major cause of morbidity and mortality among pediatric cancers in Korea as well as worldwide. Genetic variation related to …
26
Folate is involved in the one-carbon metabolism that plays an essential role in the synthesis, repair, and methylation of DNA. We examined whether child’s germline genetic …
27
… level of association was found between BHMT and BHMT2 variants, while evidence of an allelic association with CL/P was found for the single nucleotide polymorphism rs4920037, …
28
… Infatti, il genotipo eterozigote per rs4920037 nelle madri e nei figli affetti influenza il rischio di schisi. Tali risultati sono in accordo con l’evidenza che una corretta espressione di CBS sia …
29
… while in the latter study, associations to three SNPs in DMGDH (dimethylglycine dehydrogenase),(rs479405, rs1805074 and rs532964) and two SNPs in CBS (rs234705 and rs4920037…
30
… conclusion, there was an indication that lung cancer risks might be highest in those with a high %MMA who also carried cystathionine β-synthase (CBS) rs234709 and rs4920037 …
31
… , variant genotypes for CBS rs234709 and rs4920037 SNPs compared with wild-type … Small inverse associations with CBS rs234709 and rs4920037 variants were also found for …
32
An increased risk of facial clefts has been observed among mothers with lower intake of folic acid or vitamin A around conception. We hypothesized that the risk of clefts may be further …
33
Cardioembolic stroke is a complex disease resulting from the interaction of numerous factors. Using data from Genes Affecting Stroke Risk and Outcome Study (GASROS), we show that …
34
Folate metabolism pathway genes have been examined for association with neural tube defects (NTDs) because folic acid supplementation reduces the risk of this …
Curated Studies0 ▼
These studies were determined to be useful for this variant — check "Unused Studies" further down if curious what didn't make the cut.
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Unused Studies0 ▼
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