Genetics Research
rs363039
Population Frequencies12
African
G 0.59835A 0.40165GG 0.362493GA/AG 0.471723AA 0.165783pop=25,286
African American
G 0.59897A 0.40103GG 0.363429GA/AG 0.471087AA 0.165484pop=24,522
African Others
G 0.579A 0.421GG 0.332461GA/AG 0.492147AA 0.175393pop=764
Asian
G 0.4572A 0.5428GG 0.211414GA/AG 0.491569AA 0.297017pop=1,542
East Asian
G 0.4435A 0.5565GG 0.193093GA/AG 0.500785AA 0.306122pop=1,274
European
G 0.669821A 0.330179GG 0.451132GA/AG 0.437379AA 0.111489pop=269,030
Latin American 1
G 0.6378A 0.3622GG 0.413149GA/AG 0.449384AA 0.137467pop=5,354
Latin American 2
G 0.5466A 0.4534GG 0.307117GA/AG 0.479038AA 0.213845pop=6,154
Other
G 0.63816A 0.36184GG 0.414372GA/AG 0.447569AA 0.138059pop=10,242
Other Asian
G 0.522A 0.478GG 0.298507GA/AG 0.447761AA 0.253731pop=268
South Asian
G 0.6413A 0.3587GG 0.414274GA/AG 0.454147AA 0.131579pop=5,016
Studies75
Unread Studies75 ▼
1
… In addition, the overall comparison of time to ROC2 within the three groups of SNAP-25 rs363039 also revealed statistically significant differences (H = 7.623; degrees of freedom = 2; P …
2
… cognitivo evaluado mediante la Escala de Inteligencia de Wechsler para Niños-V (WISC-V), los escolares portadores de los alelos BDNF rs11030101T y SNAP25 rs363039-A …
3
Existem algumas técnicas mais específicas ligadas à tomada de decisão, como é o caso do Business Intelligence (BI), que significa negócio inteligente e visa treinar os indivíduos a …
4
Synaptic dysfunction is one of the most important markers of neurodegenerative diseases, which contribute to cognitive decline and the loss of neurons. Synaptosomal-associated …
5
… In the present child population, the SNAP25 rs363039 G/A … In agreement with this finding, the A allele of rs363039 was … Firstly, carriers of the BDNF rs11030101 T and SNAP25 rs363039 …
6
… gene (rs363050, rs363039, rs363043 and rs1051312), the authors found that patients who experienced symptoms in the first life year more frequently had the rs363039 G allele and GG …
7
Most SNPs associated with complex diseases seem to lie in non-coding regions of the genome; however, their contribution to gene expression and disease phenotype remains poorly …
8
… Additionally, we identified three genetic variants as significant risk factors for migraine susceptibility: SNAP25-rs363039’s CT genotype [OR=2.14 (95%CI: 1.36-3.34)]; the STXBP5-…
9
Este estudo investiga a contribuição genética para a inteligência através do projeto GIP-Genetic Intelligence Project, desenvolvido no Centro de Pesquisa e Análises Heráclito (CPAH). …
10
This study was performed to explore the association between attention-deficit/hyperactivity disorder (ADHD) and the risk of overweight/obesity in both children and adolescents. The …
11
An application of artificial intelligence is machine learning, which allows computer programs to learn and create data. Methods: In this work, we aimed to evaluate the …
12
… Our results showed that the SNAP-25 rs363039 G allele and GG genotype were significantly more frequent in the EO-ASD group than in the RO-ASD group in which, remarkably, the …
13
… (SNPs) of SNAP-25, described in the scientific literature as potentially relevant for neuropsychiatric disorders in a population genetically comparable to the Italian one: rs363039 (G/A), …
14
This narrative review is aimed at presenting recent evidence on the association between two widespread, chronic, and growing diseases in childhood: attention-deficit/…
15
… O SNP rs363039 localizado no intron 1 do SNAP25 foi encontrado como significativamente … O grau em que essa desativação foi observada estava relacionado ao genótipo no rs363039…
16
Borderline intellectual functioning (BIF) is a multifactorial condition in which both genetic and environmental factors are likely to contribute to the clinical outcome. Abnormal cortical …
17
of Review Attention deficit/hyperactivity disorder (ADHD) is considered as a risk factor for childhood adiposity and obesity. Studies on ADHD have provided limited data …
18
… For example, SNP rs363039 has been associated with cognitive deficits, whereas SNP rs363043 has been associated with hyperactivity traits [64,65,69,70,71]. …
19
… (rs363039 and rs2327264) to confer an increased risk for migraine compared to controls; however, only the significance of rs363039's … The rs363039 has been associated with working …
20
… Notably, rs363039 was significantly associated with PD age at onset, with the AA genotype … again showed a role for rs363039. In particular, in males, the rs363039 GG genotype was …
21
… Citation55 Indeed, test results have shown that subjects carrying the rs363050 (G) and rs363039 (A) … In rs363039, the patients who were homozygous for the minor allele (AA) exhibited …
22
… Analysis of the SNAP-25 rs363039 genotype distribution showed a significant difference among the three groups (AD versus MCI versus HC: p = 9.0×10 –3 ; df:4), and in particular, …
23
Synaptosomal Associated Protein of 25 kD (SNAP-25) is an essential protein contributing 2 out of 4 α-helices in the formation of the core soluble N-ethylmaleimide-sensitive factor …
24
The aim of the study was to assess the relationship of overweight, the polymorphisms of selected candidate genes, and deficits in the executive functions among children with …
25
The aim of this article was to review the results of research carried out in recent years in relation to genetic studies in psychiatry. The authors’ focus is on the selected disorders, with …
26
Type 2 diabetes (T2D) is a polygenic and multi-factorial complex disease. The significant challenge of finding genetic markers that could be used to predict T2D risk …
27
Available meta-analyses point to a significant association between attention-deficit/hyperactivity disorder (ADHD) and obesity. The possible mechanisms underlying this relationship are …
28
Autism spectrum disorder (ASD) is a common, complex neurological condition, affecting approximately 1% of people worldwide. Monogenic neurodevelopmental disorders which …
29
… rs363039 SNAP-25 genotypes (Figure 2 panels B and E). In particular, subjects carrying the rs363050(G) as well as the rs363039(… in subjects carrying the rs363039 minor homozygote (…
30
… Because of the pivotal role of Snap25 in insulin release [2–6] we evaluated a possible role of three Snap25 polymorphisms (rs363039, rs3630 3, and rs363050) that are localized …
31
… Because of the pivotal role of Snap25 in insulin release [2–6] we evaluated a possible role of three Snap25 polymorphisms (rs363039, rs363043, and rs363050) that are localized …
32
Attention deficit hyperactivity disorder (ADHD) is a common psychiatric condition of childhood characterized by persistent symptoms of hyperactivity, inattention, and …
33
Multiple biological processes throughout development require intracellular vesicular trafficking, where the SNARE (soluble N-ethylmaleimide-sensitive factor (NSF) attachment protein (…
34
… The authors reported a robust association between the A-allele of the SNAP25 rs363039 polymorphism and better visuospatial working memory performance in children and young …
35
A hallmark of synaptic specializations is their dependence on highly organized complexes of proteins that interact with each other. The loss or modification of key synaptic proteins …
36
… In particular, four SNAP-25 SNPs (rs363043, rs353016, rs363039 and rs363050) were associated with an increment of performance, but not of verbal intelligence quotient. …
37
… Results shown higher overall MMSE scores after rehabilitation in ApoE4 negative compared to ApoE4 positive patients, whereas the SNAP-25 rs363050 (G) and rs363039 (A) alleles …
38
… The SNPs, rs363039 of SNAP25 and rs1150 of VAMP2, were significantly associated with RCFT scores, while rs875342 of STX1A with digit span. We found genetic interaction models …
39
Synaptosomal-associated protein of 25 kDa (SNAP25) is a member of the soluble N-ethylmaleimide-sensitive factor attachment receptor (SNARE) protein complex, which …
40
We exploit recent molecular genetics evidence on the genetic basis of arsenic excretion and unique information on family links among respondents living in different environments from …
41
Synaptosomal-associated protein of 25 kDa (SNAP-25) is an age-regulated vesicular SNARE protein involved in the exocytosis of neurotransmitters from synapses, a process that is …
42
Optimism and resilience promote health and well-being in older adults, and previous reports suggest that these traits are heritable. We examined the association of selected …
43
… We found significant associations between two SNPs in the SNAP-25 gene (rs363039 and rs363050) and the shyness measured by Buss and Plomin’s EAS Temperament Survey for …
44
Attention deficit hyperactivity disorder (ADHD) is a common psychiatric condition in children worldwide that typically includes a combination of symptoms of inattention and hyperactivity/…
45
As a product of the unique evolution of the human brain, human cognitive performance is largely a collection of heritable traits. Rather surprisingly, to date there have been no reported …
46
… One of these SNPs, rs363039, is associated with working memory capacity [7]. Additional SNPs at Dde I (rs1051312) [8] and Mnl I (rs3746544) [9] can affect working, verbal, and visual …
47
The aim of the present study was to identify relations between several polymorphisms in dopamine genes (DRD2, DRD3, DRD4, SNAP-25, ANKK1 and DAT1) and temperamental …
48
The aim of the present study was to identify relations between several polymorphisms in dopamine genes (DRD2, DRD3, DRD4, SNAP-25, ANKKland DATI) and temperamental …
49
Synaptosomal-associated protein of 25 kDa (SNAP-25) is a protein that participates in the regulation of synaptic vesicle exocytosis and modulates voltage-gated calcium channels …
50
… (2008) found that the haplotype containing, among other components, the two polymorphisms we studied (rs363039 and rs363043) was related to IQ. When we consider the presented …
51
… significant genotype effect for rs363039 on verbal performances … Thus, heterozygote females for rs363039 display higher … The observation that heterozygotes for rs363039 display higher …
52
… As the selected SNPs (rs363050 and rs363039) are intronic and do not have a known functional role, we investigated whether they were associated with expression of the SNAP25 …
53
… As the selected SNPs (rs363050 and rs363039) are intronic and do not have a known functional role, we investigated whether they were associated with expression of the SNAP25 …
54
… A SNP rs363039 was found to be significantly associated with cognitive performance and functional activity in the posterior cingulated cortex in ADHD subjects [38]. …
55
… looking at the association with the rs363039 polymorphism and ADHD symptoms within the … measure as a dependent variable and rs363039, gender, rs363039*gender, and age as …
56
Alzheimer's disease (AD) is the most common cause of dementia in the elderly, and its etiology is still not fully understood. The aim of this study was to analyze the role of …
57
In the 1970s and 1980s, the government of Bangladesh, with the support and financing of the United Nations Children’s Fund, promoted the digging of tube wells to provide clean …
58
… We investigated the possibility that SNAP-25 plays a role in ASD by analyzing five SNAP-25 gene polymorphisms, rs363043, rs363039, rs363050, rs3746544 and rs1051312 in a well …
59
… Genotype at rs363039 of SNAP-25 was associated to working memory capacity and with measures of other cognitive functions in ADHD patients. In addition, this polymorphism affected …
60
Intelligence is a highly heritable trait for which it has proven difficult to identify the actual genes. In the past decade, five whole‐genome linkage scans have suggested genomic regions …
61
Zespół nadpobudliwości psychoruchowej z zaburzeniami koncentracji uwagi (atten-tion-deficit hyperactivity disorder, ADHD; według klasyfikacji DSM-IV; Diagnostic and Statistical …
62
… rs363039 on structural maturation and brain activity. (A) Interaction between genotype at rs363039 … C) Significant correlation between genotype at rs363039 and mean working memory (…
63
Synaptosomal Associated Protein 25 kDa (SNAP25) has been implicated in the pathogenesis of schizophrenia by numerous neuropathological studies and genetic variation at SNAP25 …
64
… Two new variants in intron 1 (rs363043 and rs353016), close to the two previous reported variants (rs363039 and rs363050) showed association with variation in IQ phenotypes across …
65
… In this study two single-nucleotide polymorphisms (rs363039 and rs363050) out of twelve investigated in the SNAP-25 gene showed a significant relation to standardized intelligence …
66
Abnormalities in neural connections and the neurotransmitter system appear to be involved in the pathophysiology of schizophrenia. The soluble N‐ethylmaleimide‐sensitive factor …
67
Contained within the nucleus of each mammalian diploid cell are found two genomes, a maternally and a paternally inherited copy. Recent studies have begun to better characterize the …
68
Abnormalities in neural connections and the neurotransmitter system appear to be involved in the pathophysiology of schizophrenia. The soluble N-ethylmaleimide-sensitive factor …
69
Schizophrenia is a debilitating psychiatric disorder affecting 0.5-1% of the world’s population. Schizophrenia has a significant genetic component, but the early search for specific genes …
70
… Haplotypes were estimated using the two SNPs rs363039 and rs363050 that were associated with psychometric IQ scores. Four possible haplotypes were GA, AG, GG , and AA , with …
71
… Haplotypes were estimated using the two SNPs rs363039 and rs363050 that were associated with psychometric IQ scores. Four possible haplotypes were GA, AG, GG and AA, with …
72
Opus23 Explorer™ is a fully functional version of the well-regarded and widely used Opus23 Pro™ genomic exploration software designed and programmed by Dr. Peter D'Adamo and …
73
Chairpersons: Dr SL Kate, Dr Roshan Colah 9.30 am to 9.50 am Past, Present and future of Hemoglobinopathies in India‑Dr Dipika Mohanty, Bhubaneswar 9.50 am to 10.10 am …
74
Education attainment (EA) is moderately heritable and positively related to intelligence, physical health and social and economic success. The genetic underpinnings of EA are currently …
75
… (2010) se encontró que el genotipo en rs363039, ubicado en el gen que codifica la proteína …
Curated Studies0 ▼
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Unused Studies0 ▼
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