Genetics Research
rs1928040
Population Frequencies12
African
G 0.48868A 0.51132GG 0.236557GA/AG 0.504242AA 0.259201pop=35,594
African American
G 0.48807A 0.51193GG 0.235989GA/AG 0.504154AA 0.259857pop=34,188
African Others
G 0.5036A 0.4964GG 0.250356GA/AG 0.506401AA 0.243243pop=1,406
Asian
G 0.2826A 0.7174GG 0.083109GA/AG 0.398922AA 0.517969pop=8,904
East Asian
G 0.2793A 0.7207GG 0.080011GA/AG 0.398652AA 0.521336pop=7,124
European
G 0.538098A 0.461902GG 0.290988GA/AG 0.494219AA 0.214793pop=207,912
Latin American 1
G 0.5163A 0.4837GG 0.255814GA/AG 0.521041AA 0.223145pop=3,612
Latin American 2
G 0.5153A 0.4847GG 0.264985GA/AG 0.500647AA 0.234368pop=9,276
Other
G 0.4877A 0.5123GG 0.232432GA/AG 0.510603AA 0.256965pop=4,810
Other Asian
G 0.2955A 0.7045GG 0.095506GA/AG 0.4AA 0.504494pop=1,780
South Asian
G 0.5249A 0.4751GG 0.276949GA/AG 0.495854AA 0.227197pop=1,206
Studies35
Unread Studies35 ▼
1
LIPPINCOTT WILLIAMS AND WILKINS Page 1 Genetic Variants Associated With Treatment Response in Bipolar Disorder A Systematic Review Ana Luiza da Silva Selani, Beatriz …
2
… 1, rs6311—one of the SNPs included in this study—is in high LD with rs6313 and rs1928040… reflect its strong linkage disequilibrium with rs6313 and rs1928040, which are implicated in …
3
… an association between antidepressant treatment response for MDD patients with HTR2A-rs6311 and other HTR2A gene polymorphisms such as; rs7997012, rs6313, rs1928040, …
4
… Patient-donor pairs with greater numbers of the A allele at rs1928040 showed greater increases in depression over time (p = 3.0 × 10 −4 , pFDR = 2.8 × 10 −2 ; Figure 1A); the same …
5
Knowledge of the human genome has been rapidly expanded by innovative genome sequencing and bioinformatic analysis technologies, making it possible to detect …
6
La esquizofrenia es una de las enfermedades psiquiátricas más disruptivas, la cual condiciona una discapacidad y disfunción crónica en muchos de los que la padecen; se caracteriza …
7
La depresión o Trastorno Depresivo Mayor (TDM) es un desorden del estado de ánimo que afecta a un 5% de la población mundial, aproximadamente. Debido a lo anterior, la …
8
… (rs1057910), CYP3A5 (rs776746), ABCB1 (rs1045642), CYP2C19 (rs4244285), CYP2C19 (rs4986893), CYP2C19 (rs12248560), SCL6A4 (rs25531), and 5-HTR2A (rs1928040) …
9
… (rs1057910), CYP3A5 (rs776746), ABCB1 (rs1045642), CYP2C19 (rs4244285), CYP2C19 (rs4986893), CYP2C19 (rs12248560), SCL6A4 (rs25531), and 5-HTR2A (rs1928040) …
10
Serotonin 2A receptors (HTR2A) play a crucial role in the therapeutic response to antidepressant. The activity of serotonergic system could modulate the connectivity of the …
11
Sertraline, a selective serotonin reuptake inhibitor (SSRI), is commonly prescribed to treat several psychiatric disorders including major depressive disorder (MDD), panic, generalized …
12
Prader-Willi syndrome (PWS) is a rare genetic disorder with a complex neurobehavioral phenotype associated with considerable psychiatric co-morbidity. This clinical case series, for …
13
The prevalence of mental disorders is increased among patients suffering from insulin-related somatopathies, including metabolic syndrome (MetS), obesity and type-2 diabetes (T2D). …
14
Major depressive disorder has become a prominent cause of disability, as lifetime prevalence has increased to ~15% in the Western world. Pharmacological effects of serotonin (5-…
15
В статье представлены результаты исследования возможных ассоциаций полиморфных вариантов генов серотониновых рецепторов и генов ферментов синтеза и …
16
Despite numerous studies on major depressive disorder (MDD) susceptibility, the precise underlying molecular mechanism has not been elucidated which restricts the development of …
17
Hyperprolactinaemia (HPRL) is a classical side effect of antipsychotic drugs primarily attributed to blockade of dopamine D2 subtype receptors in the pituitary gland. …
18
Serotonin reuptake inhibitors (SRIs) are often prescribed during pregnancy. Previous studies that found an increased risk of congenital anomalies, particularly congenital heart …
19
Genetic variation underlies both the response to antidepressant treatment and the occurrence of side effects. Over the past two decades, a number of pharmacogenetic variants, among …
20
Major depressive disorder (MDD) is a severe psychiatric disorder with a lifetime prevalence of approximately 10–15%. Previous pharmacological studies suggested that the …
21
Проведено исследование распределения генотипов полиморфного варианта Cys23Ser гена рецептора 2С серотонина (HTR2C) у пациентов с депрессивными …
22
Preclinical Research Central nervous system ( CNS ) disorders represent a major problem of health in developed countries, with important consequences in disability and health …
23
CNS disorders are the third major problem of health in developed countries, with approximately 10% of direct costs associated with a pharmacological treatment of doubtful cost-…
24
Inheritable factors are known to play an important role in the risk for Bipolar disorder (BD) as well as response to pharmacological treatment. In the present study, we further investigated …
25
Two serotonin 2A receptor (HTR2A) SNPs recently reported to be associated with antidepressant treatment response in STAR⁎D (rs7997012; rs1928040) were analyzed for …
26
… In this study, we detected a marginal association between rs1928040 and SSRI therapeutic … rs1928040. According to the HapMap database, MAFs of rs7997012 and rs1928040 in …
27
… Using two functional SNPs (T102C and -A1438G) and two SNPs (rs7997012 and rs1928040) in HTR2A, which reported an association with therapeutic response to the SSRI, we …
28
… , for purposes of comparison we did examine rs1928040 in HTR2A which is reported to be … to be in perfect linkage disequilibrium with it (rs1928040, rs985933), but found no evidence of …
29
… Rs6313 resides in exon 1 and rs6314 in exon 3, whereas rs7997012 and rs1928040 reside in intron 2; rs6311 is located in the 5′ untranslated region (NCBI SNP database). …
30
… , we genotyped rs7997012 and rs1928040 in the remaining … rs1928040 and treatment outcome was not substantially stronger in the total sample. Since rs7997012 and rs1928040 are …
31
Figure S2 QQ Plots-the QQ plot depicts observed versus expected quantiles for the GWAS P values, where the expected distribution of P values is uniform under the null hypothesis, …
32
Benedict Augustin Morel war der Erste, der den Begriff „Dementia praecox “verwandte. Er beschrieb damit einen Jugendlichen, der sich immer mehr zurückzog, homozide Gedanken …
33
The abstracts have not been subjected to formal peer review by the Editorial Board of I PM& R i. B Provided here are the abstracts of scientific posters presented at the 2021 Annual …
34
… В другом крупном исследовании установлена ассоциация полиморфизма rs1928040 гена HTR2A с поздней дискинезией (возникает при многолетнем приеме антипсихотиков) …
35
a depresión y sus diferentes manifestaciones, en forma de quiebra del equilibrio emocional, representan trastornos psiquiátricos de alta prevalencia en la población …
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