Genetics Research
rs1806194
Gene: GRIN2B — Glutamate Ionotropic Receptor NMDA Type Subunit 2B
Chr 12:13570193
12p13.1
Intron Variant
Population Frequencies12
African
T 0.90988C 0.09012TT 0.829462TC/CT 0.160833CC 0.009705pop=55,026
African American
T 0.90716C 0.09284TT 0.824385TC/CT 0.165555CC 0.01006pop=53,082
African Others
T 0.9841C 0.0159TT 0.968107TC/CT 0.031893CC 0pop=1,944
Asian
T 0.9675C 0.0325TT 0.938216TC/CT 0.05856CC 0.003223pop=11,168
East Asian
T 0.985C 0.015TT 0.969913TC/CT 0.030087CC 0pop=8,974
European
T 0.57563C 0.42437TT 0.331629TC/CT 0.488002CC 0.180369pop=548,420
Latin American 1
T 0.667C 0.333TT 0.444189TC/CT 0.44565CC 0.110161pop=9,586
Latin American 2
T 0.56634C 0.43366TT 0.325819TC/CT 0.481045CC 0.193136pop=17,832
Other
T 0.66417C 0.33583TT 0.452064TC/CT 0.424209CC 0.123727pop=17,878
Other Asian
T 0.8961C 0.1039TT 0.808569TC/CT 0.175023CC 0.016408pop=2,194
South Asian
T 0.7492C 0.2508TT 0.567145TC/CT 0.364072CC 0.068783pop=7,938
Studies10
Unread Studies10 ▼
1
A metilação do DNA pode mediar as interações gene-ambiente nas psicoses. O receptor N-metil-d-aspartato (NMDAR) é essencial para o neurodesenvolvimento, além de …
2
Up to 55% of patients who are administered ketamine experience an emergence phenomena (EP) that closely mimics schizophrenia and increases their risk of injury; …
3
Up to 55% of patients administered ketamine, experience an emergence phenomena (EP) that closely mimics schizophrenia and increases their risk of injury. While …
4
The GluN2B subunit of N-methyl-d-aspartate receptors is crucially involved in the physiology of the prefrontal cortex during working memory (WM). Consistently, genetic …
5
Disturbances in glutamate signaling caused by disruption of N-methyl-D-aspartate-type glutamate receptor (NMDAR) have been implicated in schizophrenia. Findings suggested that …
6
Athletes vary in their ability to recover from concussions. Following a concussion, a pathophysiological cascade of events transpires, rendering symptoms. One such event, the …
7
The dopaminergic system is known to modulate decision-making. As N-methyl-d-aspartate (NMDA) receptors strongly influence dopaminergic function, it is conceivable that the …
8
Variations in the N-methyl-d-aspartate receptor 2B subunit gene (GRIN2B) have been associated with schizophrenia, a psychiatric disorder associated with reduced left-hemispheric …
9
… In this study one SNP (rs1806194) was associated with schizophrenia in the GRIN2B gene … association with schizophrenia is in high LD with rs1806194. The level of LD between the …
10
… After Bonferroni correction, only one SNP (rs1806194) in GRIN2B remained significant. The significant interaction between GRIN2B and prenatal infection is biologically plausible …
Curated Studies0 ▼
These studies were determined to be useful for this variant — check "Unused Studies" further down if curious what didn't make the cut.
No curated studies yet.
Unused Studies0 ▼
No unused studies.