Genetics Genetics Research
CHROMOSOME 2 INTERGENIC GENE VIEW INTERGENIC ?q23 ?q25 rs11676922 — ~70,000 base pairs in the gene — ~14,000 uncommon variants · <1% of humans have them — ~1,000 common variants · >1% carry the alternate allele ALLELE STATE rs11676922 T / A · INTERGENIC HOMOZYGOUS WILD TYPE (DOMINANT) 5′ 3′ T 5′ 3′ T HETEROZYGOUS 5′ 3′ T 5′ 3′ A HOMOZYGOUS ALTERNATE (RECESSIVE) 5′ 3′ A 5′ 3′ A T Thymine — reference allele A Adenine — variant allele genetics.jdge.cc

rs11676922

Gene: INTERGENIC — Intergenic / Genome-wide Chr 2:100190478
NCBI ↗ GeneCards ↗ Open Targets ↗ gnomAD ↗ OMIM ↗ Varsome ↗ LOVD ↗

Population Frequencies12

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Total T 0.48646A 0.51354TT 0.23755TA/AT 0.497824AA 0.264625pop=24,820 ↬
African T 0.5286A 0.4714TT 0.283555TA/AT 0.490104AA 0.22634pop=5,558
African American T 0.528A 0.472TT 0.282991TA/AT 0.490093AA 0.226916pop=5,350
African Others T 0.543A 0.457TT 0.298077TA/AT 0.490385AA 0.211538pop=208
Asian T 0.386A 0.614TT 0.105263TA/AT 0.561404AA 0.333333pop=114
East Asian T 0.33A 0.67TT 0.045455TA/AT 0.568182AA 0.386364pop=88
European T 0.46734A 0.53266TT 0.216197TA/AT 0.502279AA 0.281524pop=17,114
Latin American 1 T 0.461A 0.539TT 0.201754TA/AT 0.517544AA 0.280702pop=228
Latin American 2 T 0.585A 0.415TT 0.349127TA/AT 0.471322AA 0.179551pop=802
Other T 0.513A 0.487TT 0.27051TA/AT 0.485588AA 0.243902pop=902
Other Asian T 0.58A 0.42TT 0.307692TA/AT 0.538462AA 0.153846pop=26
South Asian T 0.559A 0.441TT 0.372549TA/AT 0.372549AA 0.254902pop=102

Studies1

Unread Studies1 ▼
1

A Combination of CD28 (rs1980422) and IRF5 (rs10488631) Polymorphisms Is Associated with Seropositivity in Rheumatoid Arthritis: A Case Control Study.

Study ↗ PDF ↗
PID
A Combination of CD28 (rs1980422) and IRF5 (rs10488631) Polymorphisms Is Associated with Seropositivity in Rheumatoid Arthritis: A Case Control Study.

2016 · Vernerova L, Spoutil F, Vlcek M et al.

Curated Studies0 ▼

These studies were determined to be useful for this variant — check "Unused Studies" further down if curious what didn't make the cut.

No curated studies yet.

Unused Studies0 ▼

No unused studies.