Genetics Genetics Research
CHROMOSOME 12 GRIN2B 12p13.1 GENE VIEW GRIN2B · 12p13.1 12p14 12p12 rs11055612 — ~70,000 base pairs in the gene — ~14,000 uncommon variants · <1% of humans have them — ~1,000 common variants · >1% carry the alternate allele ALLELE STATE rs11055612 C / T · GRIN2B · 12p13.1 HOMOZYGOUS WILD TYPE (DOMINANT) 5′ 3′ C 5′ 3′ C HETEROZYGOUS 5′ 3′ C 5′ 3′ T HOMOZYGOUS ALTERNATE (RECESSIVE) 5′ 3′ T 5′ 3′ T C Cytosine — reference allele T Thymine — variant allele genetics.jdge.cc

rs11055612

Gene: GRIN2B — Glutamate Ionotropic Receptor NMDA Type Subunit 2B Chr 12:13770394 12p13.1 Intron Variant
NCBI ↗ GeneCards ↗ Open Targets ↗ gnomAD ↗ OMIM ↗ Varsome ↗ LOVD ↗

Population Frequencies12

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Total C 0.514356T 0.485644CC 0.269185CT/TC 0.490342TT 0.240473pop=355,466 ↬
African C 0.42852T 0.57148CC 0.186988CT/TC 0.483071TT 0.329941pop=41,468
African American C 0.42859T 0.57141CC 0.187196CT/TC 0.482793TT 0.330011pop=39,926
African Others C 0.4267T 0.5733CC 0.181582CT/TC 0.490272TT 0.328145pop=1,542
Asian C 0.8107T 0.1893CC 0.658433CT/TC 0.304514TT 0.037054pop=8,906
East Asian C 0.8159T 0.1841CC 0.667692CT/TC 0.296503TT 0.035804pop=7,150
European C 0.510576T 0.489424CC 0.261014CT/TC 0.499125TT 0.239861pop=279,970
Latin American 1 C 0.4995T 0.5005CC 0.24789CT/TC 0.503165TT 0.248945pop=3,792
Latin American 2 C 0.6475T 0.3525CC 0.421871CT/TC 0.451247TT 0.126882pop=8,102
Other C 0.5573T 0.4427CC 0.314866CT/TC 0.484967TT 0.200167pop=7,184
Other Asian C 0.7893T 0.2107CC 0.620729CT/TC 0.33713TT 0.042141pop=1,756
South Asian C 0.6214T 0.3786CC 0.392455CT/TC 0.457975TT 0.14957pop=6,044

Studies3

Unread Studies3 ▼
1

The influence of genes on “positive valence systems” constructs: A systematic review

Study ↗ PDF ↗
In 2009, the US National Institute of Mental Health (NIMH) proposed an approach toward the deconstruction of psychiatric nosology under the research domain criteria (RDoC) …

2016 · JL Hess, DM Kawaguchi, KE Wagner…

2

Kernel Machine Methods With Applications to High-throughout Data

Study ↗ PDF ↗
… In a linear kernel model, the number of times SNP rs11055612 being selected ranked the 16th largest out of all 119 SNPs (the corresponding rank was 13th in a Gaussian kernel), …

2015 · X Zhan

3

An adaptive genetic association test using double kernel machines

Study ↗ PDF ↗
… In a linear kernel model, the number of times SNP rs11055612 being selected ranked the 16th largest out of all 119 SNPs (the corresponding rank was 13th in a Gaussian kernel), …

2015 · X Zhan, MP Epstein, D Ghosh

Curated Studies0 ▼

These studies were determined to be useful for this variant — check "Unused Studies" further down if curious what didn't make the cut.

No curated studies yet.

Unused Studies0 ▼

No unused studies.