Folate Metabolism
The one-carbon cycle — folate transporters, methylation enzymes, DNA synthesis enzymes, and linked immune genes.
44 genes · 0 studies
ABCC1
ATP-Binding Cassette Transporter C1 (MRP1)
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ABCC2
ATP-Binding Cassette Transporter C2 (MRP2)
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ABCC3
ATP-Binding Cassette Transporter C3 (MRP3)
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ABCC4
ATP-Binding Cassette Transporter C4 (MRP4)
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ABCC5
ATP-Binding Cassette Transporter C5 (MRP5)
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ABCC6
ATP-Binding Cassette Transporter C6 (MRP6)
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ADA
Adenosine Deaminase
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AK2
Adenylate Kinase 2
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ALDH1L1
10-Formyltetrahydrofolate Dehydrogenase (cytosolic)
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ALDH1L2
10-Formyltetrahydrofolate Dehydrogenase (mitochondrial)
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ATIC
5-Aminoimidazole-4-Carboxamide Ribonucleotide Formyltransferase / IMP Cyclohydrolase
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CBS
Cystathionine Beta-Synthase
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CUBN
Cubilin
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DCLRE1C
DNA Cross-Link Repair Protein 1C (Artemis)
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DHFR
Dihydrofolate Reductase
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FOLH1
Folate Hydrolase 1 (GCPII)
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FOLR1
Folate Receptor Alpha
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FOLR2
Folate Receptor Beta
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FOLR3
Folate Receptor Gamma
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FPGS
Folylpolyglutamate Synthase
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FTCD
Formiminotransferase Cyclodeaminase
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GART
Phosphoribosylglycinamide Formyltransferase
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GGH
Gamma-Glutamyl Hydrolase
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MTFMT
Mitochondrial Methionyl-tRNA Formyltransferase
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MTHFD1
Methylenetetrahydrofolate Dehydrogenase 1 (cytosolic)
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MTHFD1L
Methylenetetrahydrofolate Dehydrogenase 1-Like
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MTHFD2
Methylenetetrahydrofolate Dehydrogenase 2 (mitochondrial)
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MTHFD2L
Methylenetetrahydrofolate Dehydrogenase 2-Like
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MTHFR
Methylenetetrahydrofolate Reductase
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MTHFS
5-Formyltetrahydrofolate Cycloligase
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MTR
Methionine Synthase
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MTRR
Methionine Synthase Reductase
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PNKP
Polynucleotide Kinase 3-Phosphatase
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RAG1
Recombination Activating Gene 1
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RAG2
Recombination Activating Gene 2
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SHMT1
Serine Hydroxymethyltransferase 1 (cytosolic)
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SHMT2
Serine Hydroxymethyltransferase 2 (mitochondrial)
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SLC19A1
Reduced Folate Carrier 1 (RFC1)
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SLC19A2
Thiamine Transporter 1 (THTR-1)
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SLC19A3
Thiamine Transporter 2 (THTR-2)
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SLC25A32
Mitochondrial Folate Transporter (MFT)
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SLC46A1
Proton-Coupled Folate Transporter (PCFT)
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TCN2
Transcobalamin II
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TYMS
Thymidylate Synthase
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