Genetics Research
Folate Metabolism
The one-carbon cycle — folate transporters, methylation enzymes, DNA synthesis enzymes, and linked immune genes.
36 genes · 2083 studies · 2083 new
ABCC1
ATP Binding Cassette Subfamily C Member 1 (ABCC1 Blood Group)
11 SNPs · 238 studies · 238 new
ABCC2
ATP Binding Cassette Subfamily C Member 2
12 SNPs · 739 studies · 739 new
ABCC3
ATP Binding Cassette Subfamily C Member 3
3 SNPs · 34 studies · 34 new
ABCC4
ATP Binding Cassette Subfamily C Member 4 (PEL Blood Group)
7 SNPs · 198 studies · 198 new
ABCC5
ATP Binding Cassette Subfamily C Member 5
1 SNP · 51 studies · 51 new
ABCC6
ATP Binding Cassette Subfamily C Member 6
4 SNPs · 14 studies · 14 new
ALDH1L1
Aldehyde Dehydrogenase 1 Family Member L1
1 SNP · 13 studies · 13 new
ALDH1L2
Aldehyde Dehydrogenase 1 Family Member L2
1 SNP
ATIC
5-Aminoimidazole-4-Carboxamide Ribonucleotide Formyltransferase/IMP Cyclohydrolase
3 SNPs · 29 studies · 29 new
CBS
Cystathionine Beta-Synthase
7 SNPs · 78 studies · 78 new
CUBN
Cubilin
3 SNPs · 31 studies · 31 new
DHFR
Dihydrofolate Reductase
3 SNPs
FOLH1
Folate Hydrolase 1
—
FOLR1
Folate Receptor Alpha
1 SNP · 1 study · 1 new
FOLR2
Folate Receptor Beta
1 SNP · 2 studies · 2 new
FOLR3
Folate Receptor Gamma
2 SNPs · 8 studies · 8 new
FPGS
Folylpolyglutamate Synthase
—
FTCD
Formimidoyltransferase Cyclodeaminase
2 SNPs
GART
Phosphoribosylglycinamide Formyltransferase, Phosphoribosylglycinamide Synthetase, Phosphoribosylaminoimidazole Synthetase
—
GGH
Gamma-Glutamyl Hydrolase
7 SNPs · 73 studies · 73 new
MTFMT
Mitochondrial Methionyl-TRNA Formyltransferase
2 SNPs · 1 study · 1 new
MTHFD1
Methylenetetrahydrofolate Dehydrogenase, Cyclohydrolase And Formyltetrahydrofolate Synthetase 1
6 SNPs · 108 studies · 108 new
MTHFD1L
Methylenetetrahydrofolate Dehydrogenase (NADP+ Dependent) 1 Like
3 SNPs · 82 studies · 82 new
MTHFD2
Methylenetetrahydrofolate Dehydrogenase (NADP+ Dependent) 2, Methenyltetrahydrofolate Cyclohydrolase
—
MTHFD2L
Methylenetetrahydrofolate Dehydrogenase (NADP+ Dependent) 2 Like
1 SNP · 1 study · 1 new
MTHFR
Methylenetetrahydrofolate Reductase
1 SNP · 41 studies · 41 new
MTHFS
Methenyltetrahydrofolate Synthetase
1 SNP · 15 studies · 15 new
MTR
5-Methyltetrahydrofolate-Homocysteine Methyltransferase
7 SNPs · 84 studies · 84 new
MTRR
5-Methyltetrahydrofolate-Homocysteine Methyltransferase Reductase
4 SNPs · 30 studies · 30 new
SHMT1
Serine Hydroxymethyltransferase 1
1 SNP
SHMT2
Serine Hydroxymethyltransferase 2
—
SLC19A1
Solute Carrier Family 19 Member 1
7 SNPs · 114 studies · 114 new
SLC25A32
Solute Carrier Family 25 Member 32
—
SLC46A1
Solute Carrier Family 46 Member 1
8 SNPs · 3 studies · 3 new
TCN2
Transcobalamin 2
1 SNP · 66 studies · 66 new
TYMS
Thymidylate Synthetase
1 SNP · 29 studies · 29 new