Folate Metabolism

The one-carbon cycle — folate transporters, methylation enzymes, DNA synthesis enzymes, and linked immune genes.

44 genes · 0 studies

ABCC1 ATP-Binding Cassette Transporter C1 (MRP1) ABCC2 ATP-Binding Cassette Transporter C2 (MRP2) ABCC3 ATP-Binding Cassette Transporter C3 (MRP3) ABCC4 ATP-Binding Cassette Transporter C4 (MRP4) ABCC5 ATP-Binding Cassette Transporter C5 (MRP5) ABCC6 ATP-Binding Cassette Transporter C6 (MRP6) ADA Adenosine Deaminase AK2 Adenylate Kinase 2 ALDH1L1 10-Formyltetrahydrofolate Dehydrogenase (cytosolic) ALDH1L2 10-Formyltetrahydrofolate Dehydrogenase (mitochondrial) ATIC 5-Aminoimidazole-4-Carboxamide Ribonucleotide Formyltransferase / IMP Cyclohydrolase CBS Cystathionine Beta-Synthase CUBN Cubilin DCLRE1C DNA Cross-Link Repair Protein 1C (Artemis) DHFR Dihydrofolate Reductase FOLH1 Folate Hydrolase 1 (GCPII) FOLR1 Folate Receptor Alpha FOLR2 Folate Receptor Beta FOLR3 Folate Receptor Gamma FPGS Folylpolyglutamate Synthase FTCD Formiminotransferase Cyclodeaminase GART Phosphoribosylglycinamide Formyltransferase GGH Gamma-Glutamyl Hydrolase MTFMT Mitochondrial Methionyl-tRNA Formyltransferase MTHFD1 Methylenetetrahydrofolate Dehydrogenase 1 (cytosolic) MTHFD1L Methylenetetrahydrofolate Dehydrogenase 1-Like MTHFD2 Methylenetetrahydrofolate Dehydrogenase 2 (mitochondrial) MTHFD2L Methylenetetrahydrofolate Dehydrogenase 2-Like MTHFR Methylenetetrahydrofolate Reductase MTHFS 5-Formyltetrahydrofolate Cycloligase MTR Methionine Synthase MTRR Methionine Synthase Reductase PNKP Polynucleotide Kinase 3-Phosphatase RAG1 Recombination Activating Gene 1 RAG2 Recombination Activating Gene 2 SHMT1 Serine Hydroxymethyltransferase 1 (cytosolic) SHMT2 Serine Hydroxymethyltransferase 2 (mitochondrial) SLC19A1 Reduced Folate Carrier 1 (RFC1) SLC19A2 Thiamine Transporter 1 (THTR-1) SLC19A3 Thiamine Transporter 2 (THTR-2) SLC25A32 Mitochondrial Folate Transporter (MFT) SLC46A1 Proton-Coupled Folate Transporter (PCFT) TCN2 Transcobalamin II TYMS Thymidylate Synthase